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Texas Rheumatology

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Heather Mambretti, PA-C

Heather Mambretti, PA-C, is a physician assistant with a background in rheumatology, previously practicing at Texas Rheumatology in League City, Texas. Since beginning her clinical career in 2011, she has provided care for patients with autoimmune and musculoskeletal conditions and collaborated with multidisciplinary teams to develop comprehensive treatment plans. While no longer in active clinical practice, Heather remains dedicated to advancing the understanding and management of rheumatologic diseases and improving patient outcomes.

Podcasts

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RhAPPcast: Unpacking the Genetics: Low ALP

March 2026
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RhAPPcast: Foundations of PMR: Diagnosis, First-Line Therapy, and Tapering Strategies

August 2025

Disease

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February 2026

FAQ: What Role Does Tissue-Nonspecific Alkaline Phosphatase (TNSALP) Play in HPP?

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September 2025

Medication Review: What Is the Safety Profile of Sarilumab in PMR & RA?

Medication
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September 2025

Medication Review: How is Sarilumab Dosed & Administered for the Treatment of PMR & RA?

Medication
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September 2025

Medication Review: Key Patient Education When Starting Sarilumab for PMR or RA

Medication
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January 2026

FAQ: How Is Hypophosphatasia Diagnosed and What Are the Key Laboratory Markers?

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November 2024

Why is Binding CD64+ Important When Discussing IL23 Directed Therapy?

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October 2024

What Is the ORAL Surveillance Study and How Can It Be Applied to Clinical Practice?

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October 2024

Provide Immunologic Rationale For IL23 Directed Therapy in PsA, PsO, and IBD.

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September 2024

Describe JAK-STAT signaling in inflammation

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